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Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt dan Venlafaxine ER

Penentuan interaksi Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt dan Venlafaxine ER dan kemungkinan penggunaannya secara bersamaan.

Hasil pengecekan:
Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt <> Venlafaxine ER
Aktualitas: 10.09.2022 Pemeriksa: Dr. P.M.Shkutko, in

Dalam database direktori resmi yang digunakan saat membuat layanan, ditemukan interaksi yang tercatat secara statistik oleh hasil penelitian, yang dapat mengarah pada konsekuensi negatif bagi kesehatan pasien, atau meningkatkan efek positif yang saling menguntungkan. Konsultasi dengan dokter diperlukan untuk menjawab masalah penggunaan obat secara bersamaan.

Konsumen:

Berbicara dengan dokter anda sebelum menggunakan dekstrometorfan bersama-sama dengan venlafaxine. Menggabungkan obat-obat ini dapat meningkatkan risiko yang serius, namun jarang terjadi kondisi yang disebut sindrom serotonin, yang dapat mencakup gejala-gejala seperti kebingungan, halusinasi, kejang, perubahan ekstrim dalam tekanan darah, peningkatan denyut jantung, demam, keringat berlebihan, menggigil atau gemetar, penglihatan kabur, kejang otot atau kekakuan, tremor, inkoordinasi, kram perut, mual, muntah, dan diare. Kasus yang parah dapat menyebabkan koma dan bahkan kematian. Anda harus menghubungi dokter anda segera jika anda mengalami gejala-gejala saat mengambil obat. Hal ini penting untuk memberitahu dokter anda tentang semua obat lain yang anda gunakan, termasuk vitamin dan rempah-rempah. Jangan berhenti menggunakan obat apapun tanpa terlebih dahulu berbicara dengan dokter anda.

Profesional:

MEMONITOR: penggunaan Bersamaan dari agen dengan aktivitas serotonergik seperti serotonin reuptake inhibitor, inhibitor monoamine oxidase inhibitor, antidepresan trisiklik, 5-HT1 agonis reseptor, ergot alkaloid, lithium, St John wort, phenylpiperidine opioid, dekstrometorfan, dan triptofan dapat mempotensiasi risiko sindrom serotonin, yang jarang namun serius dan berpotensi fatal diduga hasil dari hiperstimulasi dari batang otak 5-HT1A dan 2A reseptor. Gejala sindrom serotonin dapat mencakup perubahan status mental seperti mudah marah, gangguan kesadaran, kebingungan, halusinasi, dan koma; disfungsi otonom seperti takikardia, hipertermia, diaphoresis, menggigil, tekanan darah labil, dan midriasis; kelainan neuromuskuler seperti hyperreflexia, myoclonus, tremor, kekakuan, dan ataksia; dan gejala pada saluran pencernaan seperti kram perut, mual, muntah, dan diare.

MANAJEMEN: Secara umum, penggunaan bersamaan dari beberapa agen serotonergik harus dihindari jika mungkin, atau jika tidak didekati dengan hati-hati jika potensi manfaat yang dianggap lebih besar daripada risiko. Beberapa produsen mempertimbangkan penggunaan bersamaan dekstrometorfan dan selective serotonin reuptake inhibitor dikontraindikasikan. Jika terapi bersamaan diperlukan, pasien harus dipantau secara ketat untuk gejala sindrom serotonin selama pengobatan. Tertentu disarankan untuk hati-hati ketika meningkatkan dosis dari agen ini. Potensi risiko untuk sindrom serotonin harus dipertimbangkan bahkan ketika pemberian agen serotonergik secara berurutan, seperti beberapa agen dapat menunjukkan berkepanjangan paruh eliminasi (misalnya, fluoxetine). Jika sindrom serotonin berkembang atau diduga selama terapi, semua serotonergik agen harus dihentikan segera dan perawatan suportif yang diberikan seperti yang diperlukan. Cukup sakit pasien juga dapat mengambil manfaat dari pemberian serotonin antagonis (misalnya, siproheptadin, klorpromazin). Kasus yang parah harus dikelola di bawah konsultasi dengan toksikologi dan mungkin memerlukan sedasi, neuromuskuler kelumpuhan, intubasi dan ventilasi mekanis di samping langkah-langkah lain.

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Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt

Nama generik: acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine

Nama merek: Comtrex Cold and Flu Maximum Strength Tablet, Robitussin Flu, Theraflu Cold & Cough, Theraflu Flu & Cough, Theraflu Severe Cold & Congestion, Triaminic Cold and Fever, Vicks 44 Cold, Flu and Cough, EQL Severe Cold/Flu, Theracaps Cough/Cold Reliever, Tylenol Cold, Children’s Non-Aspirin Cold/Cough, EQL Pain Relief Plus Cold/Cough, Tylenol Children’s Cold/Cough

Sinonim: Acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine

Apa itu Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt?
Venlafaxine ER

Nama generik: venlafaxine

Nama merek: Effexor XR, Effexor

Sinonim: Venlafaxine

Apa itu Venlafaxine ER?
+ Tambah obat Hapus semua

Dalam proses pemeriksaan kompatibilitas dan interaksi obat, digunakan data referensi tersebut: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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  1. Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt
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  1. Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine Powder Pkt
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