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Insulin degludec and liraglutide dan Zyvox (Linezolid Suspension)

Penentuan interaksi Insulin degludec and liraglutide dan Zyvox (Linezolid Suspension) dan kemungkinan penggunaannya secara bersamaan.

Hasil pengecekan:

Insulin degludec and liraglutide <> Zyvox (Linezolid Suspension)

Aktualitas: 19.10.2022 Pemeriksa: Dr. P.M.Shkutko, in

Dalam database direktori resmi yang digunakan saat membuat layanan, ditemukan interaksi yang tercatat secara statistik oleh hasil penelitian, yang dapat mengarah pada konsekuensi negatif bagi kesehatan pasien, atau meningkatkan efek positif yang saling menguntungkan. Konsultasi dengan dokter diperlukan untuk menjawab masalah penggunaan obat secara bersamaan.

Konsumen:

Menggunakan linezolid bersama-sama dengan insulin atau tertentu lainnya obat diabetes dapat meningkatkan risiko hipoglikemia atau gula darah rendah. Gejala hipoglikemia termasuk sakit kepala, pusing, mengantuk, kegelisahan, kebingungan, tremor, mual, lapar, lemas, berkeringat, palpitasi, dan detak jantung yang cepat. Bicarakan dengan dokter anda jika anda memiliki pertanyaan atau masalah. Anda mungkin memerlukan penyesuaian dosis atau pemantauan lebih sering gula darah anda dengan aman menggunakan obat-obatan. Hal ini penting untuk memberitahu dokter anda tentang semua obat lain yang anda gunakan, termasuk vitamin dan rempah-rempah. Jangan berhenti menggunakan obat apapun tanpa terlebih dahulu berbicara dengan dokter anda.

Profesional:

MONITOR: efek hipoglikemik dari insulin yang dapat ditimbulkan oleh obat-obatan tertentu seperti ACE inhibitor, angiotensin receptor blocker (Arb), amylin analog, steroid anabolik, fibrat, inhibitor monoamine oxidase (MAOIs, termasuk linezolid), salisilat, selective serotonin reuptake inhibitor (Ssri), sulfonamid, disopiramid, propoxyphene, quinidine, kina, dan ginseng. Obat ini dapat meningkatkan risiko hipoglikemia dengan meningkatkan sensitivitas insulin (ACE inhibitor, Arb, fibrat, ginseng); merangsang sekresi insulin (salisilat, disopiramid, pentoxifylline, propoxyphene, quinidine, kina, MAOIs, ginseng); meningkatkan pemanfaatan glukosa perifer (Ssri, insulin-seperti faktor pertumbuhan); menghambat glukoneogenesis (Ssri, MAOIs, insulin-seperti faktor pertumbuhan); memperlambat laju pengosongan lambung (amylin analog); dan/atau menekan postprandial sekresi glukagon (amylin analog). Klinis hipoglikemia telah dilaporkan selama penggunaan agen-agen ini sendiri atau dengan insulin dan/atau sekretagog insulin. Penggunaan Ssri juga telah dikaitkan dengan hilangnya kesadaran hipoglikemia pada kasus-kasus yang terisolasi.

MANAJEMEN: pemantauan ketat untuk pengembangan hipoglikemia dianjurkan jika obat ini diberikan bersama insulin, terutama pada pasien dengan usia lanjut dan/atau gangguan ginjal. Dosis insulin mungkin memerlukan penyesuaian jika interaksi dicurigai. Pasien harus diberitahu tentang tanda-tanda dan gejala hipoglikemia (misalnya, sakit kepala, pusing, mengantuk, mual, kelaparan, tremor, kelemahan, berkeringat, berdebar-debar), cara untuk mengobatinya, dan untuk menghubungi dokter mereka jika hal itu terjadi. Pasien harus diamati untuk kehilangan kontrol glikemik ketika obat ini ditarik.

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